User blog comment:Meshifuari Arimota/Devil May Cry V/@comment-33329977-20180608154444/@comment-32167062-20180610225324

Well, Dante did defeat Nelo Angelo, who looked somewhat simmilar to Vergil (not similar enough for Dante to recognise him instantly), had his half of the Amulet... and diappeared after being defeated.

And we know that Mundus was able to create demons with appearances almost, if not completely identical to someone else, (for example Trish)

as for the timeline, Nero looking a lot different might point to after DMC2.

About nero loosing his arm: it seems that his prosthetic has at least simmilar capabilities, and gameplay-wise will be mostly the same, maybe with more gimmics.