This is a list of all available PS3 Trophies and Xbox 360 Achievements for the HD version of Devil May Cry 2.
| Award | Image | Description | Gamerscore | Trophy |
| Every Knee Will Bend | 
|
Finish the game on Normal Mode with any character | 10 
|
|
| Every Head Will Bow | 
|
Finish the game on Hard Mode with any character | 20
|
|
| Every Tongue Will Confess | 
|
Finish the game on Must Die Mode with any character | 40
|
|
| Barehand Beauty | 
|
Finish the game on any difficulty with Trish | 15
|
|
| A Secret Revealed | 
|
Complete a Secret Mission | 5
|
|
| First Blood | 
|
Pass 1000 levels in Bloody Palace Mode | 5
|
|
| Blood Letting | 
|
Pass 5000 floors in Bloody Palace Mode | 10
|
|
| Over 9000! | 
|
Pass 9000 floors in Bloody Palace Mode | 20
|
|
| Highest Honor | 
|
Achieve an S Rank on any Mission with Dante | 5
|
|
| The Sky's The Limit | 
|
Achieve an S Rank on any Mission with Lucia | 5
|
|
| Vita Maxima | 
|
Max out Health Bar with any character | 10
|
|
| Magica Maxima | 
|
Max out Devil Trigger Gauge with any character | 10
|
|
| Caeruleus Diabolus | 
|
Collect 12 Blue Orb Fragments (Dante/Lucia) | 10
|
|
| Two Heads are Better Than One | 
|
Defeat Tartarussian | 5
|
|
| Monkeying Around | 
|
Defeat Orangguerra | 5
|
|
| No Joke | 
|
Defeat Jokatgulm | 5
|
|
| Sin City | 
|
Defeat Nefasturris | 5
|
|
| Deep One | 
|
Defeat Tateobesu | 5
|
|
| That's A Big Mother... | 
|
Defeat Noctpteran | 5
|
|
| Hungry Like the Wolves | 
|
Defeat Bolverk | 5
|
|
| Ball 'n Chain | 
|
Defeat Plutonian | 5
|
|
| Not Just Any Ordinary Human | 
|
Defeat Phantom | 5
|
|
| Never Forget a Face | 
|
Defeat Trismagia | 5
|
|
| Extinguished | 
|
Defeat the final boss with either Dante or Lucia | 5
|
|
| Stylish! | 
|
Perform an S Rank Combo using Dante | 5
|
|
| En Vogue | 
|
Perform an S Rank Combo using Lucia | 5
|
|
| Armed and Dangerous | 
|
Reach Level 3 on any Sword with Lucia | 10
|
|
| Arms Race | 
|
Reach Level 3 on any Gun with Dante | 10
|
|
| Like A Hot Knife Through Butter | 
|
Reach Level 3 on all Swords with Dante | 20
|
|
| To The Max | 
|
Reach Level 3 on all Arsenals with Lucia | 20
|
|
| Full Armory | 
|
Collect all Swords with Dante | 10
|
|
| Check Out My Collection | 
|
Collect all Arsenals with Lucia | 10
|
|
| Take Heart, Lucia | 
|
Collect all Devil Hearts with Lucia | 10
|
|
| Platinum Trophy | 
|
Unlock all trophies | N/A | 
|